I105V (p.Ile105Val) variant of TYK2 (P29597)
I105V (p.Ile105Val) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I105V (p.Ile105Val) variant details
- p.Ile105Val
- TOPMed rs1029569489
- gnomAD rs1029569489
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.06
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available