H62Y (p.His62Tyr) variant of TYK2 (P29597)
H62Y (p.His62Tyr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H62Y (p.His62Tyr) variant details
- p.His62Tyr
- TOPMed rs1434247208
- gnomAD rs1434247208
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.06
- CADD 16.40
- PolyPhen-2 0.16
- SIFT 0.02
- Most common in the HGDP:DAI population (allele frequency 0.056)
- Structural context available