G7E (p.Gly7Glu) variant of TYK2 (P29597)
G7E (p.Gly7Glu) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G7E (p.Gly7Glu) variant details
- p.Gly7Glu
- ExAC rs771091357
- gnomAD rs771091357
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.13
- CADD 14.80
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available