G39V (p.Gly39Val) variant of TYK2 (P29597)
G39V (p.Gly39Val) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G39V (p.Gly39Val) variant details
- p.Gly39Val
- ExAC rs766133942
- TOPMed rs766133942
- gnomAD rs766133942
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.24
- CADD 11.70
- PolyPhen-2 0.37
- SIFT 0.06
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available