G11V (p.Gly11Val) variant of TYK2 (P29597)
G11V (p.Gly11Val) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G11V (p.Gly11Val) variant details
- p.Gly11Val
- gnomAD rs900008134
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.18
- CADD 11.00
- PolyPhen-2 0.16
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available