G11D (p.Gly11Asp) variant of TYK2 (P29597)
G11D (p.Gly11Asp) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G11D (p.Gly11Asp) variant details
- p.Gly11Asp
- gnomAD rs900008134
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.28
- CADD 3.97
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available