E169G (p.Glu169Gly) variant of TYK2 (P29597)
E169G (p.Glu169Gly) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
E169G (p.Glu169Gly) variant details
- p.Glu169Gly
- TOPMed rs1478105936
- gnomAD rs1478105936
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.12
- CADD 24.20
- PolyPhen-2 0.07
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available