A81T (p.Ala81Thr) variant of TYK2 (P29597)
A81T (p.Ala81Thr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A81T (p.Ala81Thr) variant details
- p.Ala81Thr
- ExAC rs752941433
- TOPMed rs752941433
- gnomAD rs752941433
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.08
- CADD 18.20
- PolyPhen-2 0.02
- SIFT 0.40
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available