A81S (p.Ala81Ser) variant of TYK2 (P29597)
A81S (p.Ala81Ser) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A81S (p.Ala81Ser) variant details
- p.Ala81Ser
- ExAC rs752941433
- TOPMed rs752941433
- gnomAD rs752941433
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.03
- CADD 17.30
- PolyPhen-2 0.02
- SIFT 0.48
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available