A35T (p.Ala35Thr) variant of TYK2 (P29597)
A35T (p.Ala35Thr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A35T (p.Ala35Thr) variant details
- p.Ala35Thr
- TOPMed rs1335649847
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.06
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available