A132V (p.Ala132Val) variant of TYK2 (P29597)
A132V (p.Ala132Val) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A132V (p.Ala132Val) variant details
- p.Ala132Val
- TOPMed rs2041750912
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.05
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available