P59T (p.Pro59Thr) variant of TULP1 (Tubby-related protein 1)
P59T (p.Pro59Thr) in TULP1 (Tubby-related protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P59T (p.Pro59Thr) variant details
- p.Pro59Thr
- ExAC rs755762321
- TOPMed rs755762321
- gnomAD rs755762321
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.24
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 26.10
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available