R105G (p.Arg105Gly) variant of TUBA1A (Tubulin alpha-1A chain)
R105G (p.Arg105Gly) in TUBA1A (Tubulin alpha-1A chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
R105G (p.Arg105Gly) variant details
- p.Arg105Gly
- gnomAD rs1237540680
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.83
- MetaLR 0.66
- MetaSVM 0.51
- CADD 28.30
- PolyPhen-2 0.82
- SIFT 0.00
- Population evidence available
- Structural context available