F53F (p.Phe53Phe) variant of TUBA1A (Tubulin alpha-1A chain)
F53F (p.Phe53Phe) in TUBA1A (Tubulin alpha-1A chain) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
F53F (p.Phe53Phe) variant details
- p.Phe53Phe
- rs1281750454
- gnomAD 12-49186678-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.271
- CADD 14.60
- SIFT 0.14
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.12)
- Structural context available
- Literature evidence available