V15L (p.Val15Leu) variant of TTR (Transthyretin)
V15L (p.Val15Leu) in TTR (Transthyretin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- gnomAD 18-31591945-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.23
- MetaLR 0.77
- MetaSVM 0.51
- CADD 20.20
- PolyPhen-2 0.01
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available