T60S (p.Thr60Ser) variant of TTR (Transthyretin)
T60S (p.Thr60Ser) in TTR (Transthyretin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
T60S (p.Thr60Ser) variant details
- p.Thr60Ser
- gnomAD 18-31593005-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.19
- MetaLR 0.57
- MetaSVM -0.42
- CADD 2.43
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available