P22S (p.Pro22Ser) variant of TTR (Transthyretin)
P22S (p.Pro22Ser) in TTR (Transthyretin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
P22S (p.Pro22Ser) variant details
- p.Pro22Ser
- gnomAD 18-31591966-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.29
- MetaLR 0.79
- MetaSVM 0.28
- CADD 15.10
- PolyPhen-2 0.08
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available