L11F (p.Leu11Phe) variant of TTR (Transthyretin)
L11F (p.Leu11Phe) in TTR (Transthyretin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data, published literature, and structural context.
L11F (p.Leu11Phe) variant details
- p.Leu11Phe
- gnomAD 18-31591933-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.747
- REVEL 0.67
- MetaLR 0.93
- MetaSVM 1.01
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available