R17G (p.Arg17Gly) variant of TSHR (Thyrotropin receptor)
R17G (p.Arg17Gly) in TSHR (Thyrotropin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R17G (p.Arg17Gly) variant details
- p.Arg17Gly
- gnomAD rs1470956073
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.14
- CADD 3.68
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available