G20S (p.Gly20Ser) variant of TSHR (Thyrotropin receptor)
G20S (p.Gly20Ser) in TSHR (Thyrotropin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G20S (p.Gly20Ser) variant details
- p.Gly20Ser
- cosmic curated COSV10814
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.19
- CADD 1.33
- PolyPhen-2 0.08
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available