P45T (p.Pro45Thr) variant of TRPM4 (Q8TD43)
P45T (p.Pro45Thr) in TRPM4 (Q8TD43) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P45T (p.Pro45Thr) variant details
- p.Pro45Thr
- ExAC rs765781527
- TOPMed rs765781527
- gnomAD rs765781527
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.12
- ESM-1b 0.00
- AlphaMissense 0.07
- CADD 0.69
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available