I24T (p.Ile24Thr) variant of TRPM4 (Q8TD43)
I24T (p.Ile24Thr) in TRPM4 (Q8TD43) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
I24T (p.Ile24Thr) variant details
- p.Ile24Thr
- Ensembl rs1568450327
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.42
- ESM-1b 0.00
- AlphaMissense 0.22
- CADD 23.70
- PolyPhen-2 0.12
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available