G32E (p.Gly32Glu) variant of TRPM4 (Q8TD43)
G32E (p.Gly32Glu) in TRPM4 (Q8TD43) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- gnomAD 19-49166043-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.13
- CADD 26.30
- PolyPhen-2 0.95
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available