G32A (p.Gly32Ala) variant of TRPM4 (Q8TD43)
G32A (p.Gly32Ala) in TRPM4 (Q8TD43) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- ExAC rs772015839
- gnomAD rs772015839
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.13
- ESM-1b 0.00
- AlphaMissense 0.13
- CADD 23.80
- PolyPhen-2 0.66
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available