R5W (p.Arg5Trp) variant of TRMU (O75648)
R5W (p.Arg5Trp) in TRMU (O75648) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
R5W (p.Arg5Trp) variant details
- p.Arg5Trp
- TOPMed rs2077953982
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.66
- ESM-1b 1.00
- AlphaMissense 0.67
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:JAPANESE population (allele frequency 0.018)
- Structural context available