R25M (p.Arg25Met) variant of TRMU (O75648)
R25M (p.Arg25Met) in TRMU (O75648) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
R25M (p.Arg25Met) variant details
- p.Arg25Met
- gnomAD 22-46335838-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.38
- MetaLR 0.21
- MetaSVM -0.83
- CADD 23.90
- Most common in the Non-Finnish European population (allele frequency 0.00046)
- Structural context available
- Literature evidence available