L22M (p.Leu22Met) variant of TRMU (O75648)
L22M (p.Leu22Met) in TRMU (O75648) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
L22M (p.Leu22Met) variant details
- p.Leu22Met
- gnomAD 22-46335828-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.30
- ESM-1b 1.00
- AlphaMissense 0.24
- MetaLR 0.41
- MetaSVM -0.16
- CADD 26.70
- Population evidence available
- Structural context available
- Literature evidence available