A20S (p.Ala20Ser) variant of TRMU (O75648)
A20S (p.Ala20Ser) in TRMU (O75648) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
A20S (p.Ala20Ser) variant details
- p.Ala20Ser
- gnomAD 22-46335822-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.28
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.20
- MetaSVM -0.83
- CADD 22.80
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available