T13S (p.Thr13Ser) variant of TREX1 (Three-prime repair exonuclease 1)
T13S (p.Thr13Ser) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
T13S (p.Thr13Ser) variant details
- p.Thr13Ser
- gnomAD rs1287600584
- Missense
- Variant Prioritization Score for Impact Estimate 0.428
- CADD 21.50
- PolyPhen-2 0.10
- SIFT 0.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available