T13P (p.Thr13Pro) variant of TREX1 (Three-prime repair exonuclease 1)
T13P (p.Thr13Pro) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
T13P (p.Thr13Pro) variant details
- p.Thr13Pro
- gnomAD rs1287600584
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- CADD 26.20
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available