S3S (p.Ser3Ser) variant of TREX1 (Three-prime repair exonuclease 1)
S3S (p.Ser3Ser) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
S3S (p.Ser3Ser) variant details
- p.Ser3Ser
- rs762687506
- gnomAD 3-48466664-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0849
- CADD 0.61
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available