S27S (p.Ser27Ser) variant of TREX1 (Three-prime repair exonuclease 1)
S27S (p.Ser27Ser) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
S27S (p.Ser27Ser) variant details
- p.Ser27Ser
- rs1308074815
- gnomAD 3-48466736-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.667
- CADD 11.20
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available