P8P (p.Pro8Pro) variant of TREX1 (Three-prime repair exonuclease 1)
P8P (p.Pro8Pro) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P8P (p.Pro8Pro) variant details
- p.Pro8Pro
- rs147463121
- gnomAD 3-48466679-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0814
- CADD 0.15
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available