P61S (p.Pro61Ser) variant of TREX1 (Three-prime repair exonuclease 1)
P61S (p.Pro61Ser) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
P61S (p.Pro61Ser) variant details
- p.Pro61Ser
- gnomAD rs1449073652
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available