P25P (p.Pro25Pro) variant of TREX1 (Three-prime repair exonuclease 1)
P25P (p.Pro25Pro) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
P25P (p.Pro25Pro) variant details
- p.Pro25Pro
- gnomAD 3-48466730-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.549
- CADD 11.60
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available