P10S (p.Pro10Ser) variant of TREX1 (Three-prime repair exonuclease 1)
P10S (p.Pro10Ser) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P10S (p.Pro10Ser) variant details
- p.Pro10Ser
- cosmic curated COSV10733
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- CADD 15.80
- PolyPhen-2 0.12
- SIFT 0.13
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available