L24L (p.Leu24Leu) variant of TREX1 (Three-prime repair exonuclease 1)
L24L (p.Leu24Leu) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L24L (p.Leu24Leu) variant details
- p.Leu24Leu
- rs768580583
- gnomAD 3-48466725-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.404
- CADD 12.10
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available