L24F (p.Leu24Phe) variant of TREX1 (Three-prime repair exonuclease 1)
L24F (p.Leu24Phe) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L24F (p.Leu24Phe) variant details
- p.Leu24Phe
- ExAC rs780921510
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available