G2S (p.Gly2Ser) variant of TREX1 (Three-prime repair exonuclease 1)
G2S (p.Gly2Ser) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G2S (p.Gly2Ser) variant details
- p.Gly2Ser
- TOPMed rs2040318477
- gnomAD rs2040318477
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- CADD 22.10
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available