G2G (p.Gly2Gly) variant of TREX1 (Three-prime repair exonuclease 1)
G2G (p.Gly2Gly) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
G2G (p.Gly2Gly) variant details
- p.Gly2Gly
- rs1457063888
- gnomAD 3-48466661-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.488
- CADD 11.40
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available