F26V (p.Phe26Val) variant of TREX1 (Three-prime repair exonuclease 1)
F26V (p.Phe26Val) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
F26V (p.Phe26Val) variant details
- p.Phe26Val
- ExAC rs772753856
- gnomAD rs772753856
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- CADD 21.50
- PolyPhen-2 0.37
- SIFT 0.49
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available