F26S (p.Phe26Ser) variant of TREX1 (Three-prime repair exonuclease 1)
F26S (p.Phe26Ser) in TREX1 (Three-prime repair exonuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
F26S (p.Phe26Ser) variant details
- p.Phe26Ser
- cosmic curated COSV10517
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- CADD 16.80
- PolyPhen-2 0.01
- SIFT 0.94
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available