F17F (p.Phe17Phe) variant of TREX1 (Three-prime repair exonuclease 1)
F17F (p.Phe17Phe) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
F17F (p.Phe17Phe) variant details
- p.Phe17Phe
- rs1252848366
- gnomAD 3-48466706-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.374
- CADD 13.40
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available