D18D (p.Asp18Asp) variant of TREX1 (Three-prime repair exonuclease 1)
D18D (p.Asp18Asp) in TREX1 (Three-prime repair exonuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D18D (p.Asp18Asp) variant details
- p.Asp18Asp
- gnomAD 3-48466709-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.403
- CADD 12.70
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available