T2S (p.Thr2Ser) variant of TRDN (Triadin)
T2S (p.Thr2Ser) in TRDN (Triadin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T2S (p.Thr2Ser) variant details
- p.Thr2Ser
- gnomAD rs1484432039
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.18
- CADD 26.30
- PolyPhen-2 0.88
- SIFT 0.02
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available