K83N (p.Lys83Asn) variant of TRDN (Triadin)
K83N (p.Lys83Asn) in TRDN (Triadin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
K83N (p.Lys83Asn) variant details
- p.Lys83Asn
- NCI-TCGA Cosmic COSV1005
- cosmic curated COSV10052
- NCI-TCGA Cosmic COSV6212
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.28
- CADD 25.20
- PolyPhen-2 0.93
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.9e-05)
- Structural context available