V58I (p.Val58Ile) variant of TRAF6 (TNF receptor-associated factor 6)
V58I (p.Val58Ile) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
V58I (p.Val58Ile) variant details
- p.Val58Ile
- gnomAD rs1179758607
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.41
- MetaLR 0.43
- MetaSVM -0.24
- CADD 22.20
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available