V36M (p.Val36Met) variant of TRAF6 (TNF receptor-associated factor 6)
V36M (p.Val36Met) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
V36M (p.Val36Met) variant details
- p.Val36Met
- ExAC rs750708011
- TOPMed rs750708011
- gnomAD rs750708011
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.32
- MetaLR 0.50
- MetaSVM 0.21
- CADD 20.50
- PolyPhen-2 0.28
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available