V30A (p.Val30Ala) variant of TRAF6 (TNF receptor-associated factor 6)
V30A (p.Val30Ala) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
V30A (p.Val30Ala) variant details
- p.Val30Ala
- gnomAD rs1379813834
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.16
- MetaLR 0.15
- MetaSVM -0.94
- CADD 8.19
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available