T83M (p.Thr83Met) variant of TRAF6 (TNF receptor-associated factor 6)
T83M (p.Thr83Met) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
T83M (p.Thr83Met) variant details
- p.Thr83Met
- cosmic curated COSV61923
- 1000Genomes rs199552714
- ExAC rs199552714
- Missense
- Variant Prioritization Score for Impact Estimate 0.791
- REVEL 0.80
- MetaLR 0.76
- MetaSVM 0.63
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available